Journal: Epilepsia Open

Article Title: Intrinsic brain network stability during kainic acid‐induced epileptogenesis

doi: 10.1002/epi4.70002

Figure Lengend Snippet: (A) The within‐network reliability analysis across three experimental trials (Trials 1, 2, and 3: BOLD‐fMRI scan at Days 0–1, Days 2–3, and Days 4–5, respectively) was assessed by the MN sub‐networks in the sham control group. No significant difference was observed in any sub‐networks. (B). The within‐network reliability across three trials was assessed by the MN sub‐networks in the KA group. A significantly large ICA intensity was observed in Trial 2 vs. Trial 1 in the PrR, Trial 2 vs. Trial 1 in the DHpL, and Trial 3 vs. Trial 2 in the DHpR. One asterisk (*) identifies adjusted P values lower than 0.1. (C). Intraclass correlation coefficient (ICC) reflects the test–retest reliability in four MN sub‐networks in the sham rats and KA rats. It indicated a low‐to‐excellent reliability in sham, while the average reliability dropped in the KA group.

Article Snippet: Group‐level BOLD‐fMRI data were analyzed using GICA in the Group ICA of FMRI Toolbox (GIFT) Matlab software to identify MNs during brain resting state.

Techniques: Control

Journal: Biomedical Optics Express

Article Title: Out-of-focus signal rejection for in vivo pO 2 measurements using two-photon phosphorescence lifetime microscopy

doi: 10.1364/BOE.532084

Figure Lengend Snippet: Configuration of the 2PLM imaging setup with an LC-SLM. M1- M7: mirrors; HWP: half-wave plate; P: polarizer; EOM: electro-optic modulator; SH: shutter; PH: pinhole; L1 - L4: lenses; LC-SLM: liquid crystal spatial light modulator; IR: iris diaphragm; GM: galvo mirrors; SL: scan lens; TL: tube lens; DM: dichroic mirror; OL: objective lens (20X); EFs: emission filters; PMTs: photomultiplier tubes; CAM: CMOS camera. The vortex mask (topological charge m = 5 used as an example) is combined with a blazed grating mask when projected onto the LC-SLM to separate the torus focal spot (1 st order) from the 0 th order of LC-SLM diffraction.

Article Snippet: The MATLAB-based control software of 2PLM used in the work is also available online [ ].

Techniques: Imaging

Journal: Biomedical Optics Express

Article Title: Out-of-focus signal rejection for in vivo pO 2 measurements using two-photon phosphorescence lifetime microscopy

doi: 10.1364/BOE.532084

Figure Lengend Snippet: Examples of in vivo phosphorescence lifetime measurements for intravascular pO 2 from various locations in pial arterioles and venules obtained using 2PLM. (a) A survey image was acquired to select pO 2 imaging locations. Two locations (1 and 2) were selected in arterioles, and the other two locations (3 and 4) were selected in venules. Scale bar: 100 µm. P.C.: Photon counts. (b) Phosphorescence decays (dotted lines) acquired from the selected four locations in (a) with 2000 laser excitation cycles, and their corresponding lifetime and pO 2 values.

Article Snippet: The MATLAB-based control software of 2PLM used in the work is also available online [ ].

Techniques: In Vivo, Imaging